Conversion of raft associated prion protein to the protease-resistant state requires insertion of PrP-res (PrP(Sc)) into contiguous membranes

Prion protein (PrP) is usually attached to membranes by a glycosylphosphatidylinositol-anchor that associates with detergent-resistant membranes (DRMs), or rafts. To model the molecular processes that might occur during the initial infection of cells with exogenous transmissible spongiform encephalo...

Full beskrivning

Bibliografiska uppgifter

I publikationen:	EMBO J
Huvudupphov:	Baron, Gerald S., Wehrly, Kathy, Dorward, David W., Chesebro, Bruce, Caughey, Byron
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Nature Publishing Group 2002
Ämnen:	Article
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125906/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11867531/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.5.1031
Taggar:	Lägg till en tagg Inga taggar, Lägg till första taggen!