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Conversion of raft associated prion protein to the protease-resistant state requires insertion of PrP-res (PrP(Sc)) into contiguous membranes

Prion protein (PrP) is usually attached to membranes by a glycosylphosphatidylinositol-anchor that associates with detergent-resistant membranes (DRMs), or rafts. To model the molecular processes that might occur during the initial infection of cells with exogenous transmissible spongiform encephalo...

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Bibliografski detalji
Glavni autori: Baron, Gerald S., Wehrly, Kathy, Dorward, David W., Chesebro, Bruce, Caughey, Byron
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC125906/
https://ncbi.nlm.nih.gov/pubmed/11867531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.5.1031
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