Binding of the protease-sensitive form of PrP (prion protein) to sulfated glycosaminoglycan and congo red [corrected]

Congo red and certain sulfated glycans are potent inhibitors of protease-resistant PrP accumulation in scrapie-infected cells. One hypothesis is that these inhibitors act by blocking the association between protease-resistant PrP and sulfated glycosaminoglycans or proteoglycans (e.g., heparan sulfat...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Caughey, B, Brown, K, Raymond, G J, Katzenstein, G E, Thresher, W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236688/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7511169/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.4.2135-2141.1994
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