A carregar...
BRIT1/MCPH1 is a DNA damage responsive protein that regulates the Brca1–Chk1 pathway, implicating checkpoint dysfunction in microcephaly
BRIT1 [BRCT-repeat inhibitor of hTERT expression], a repressor of human telomerase function, is implicated in cellular immortalization. Here, we find that BRIT1 acts as a regulator of both the intra-S and G(2)/M checkpoints. When BRIT1 expression is depleted, cells lose the ionizing radiation (IR)-i...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1257745/ https://ncbi.nlm.nih.gov/pubmed/16217032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507722102 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|