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Multiple Roles of BRIT1/MCPH1 in DNA Damage Response, DNA Repair, and Cancer Suppression

Mammalian cells are frequently at risk of DNA damage from both endogenous and exogenous sources. Accordingly, cells have evolved the DNA damage response (DDR) pathways to monitor and assure the integrity of their genome. In cells, the intact and effective DDR is essential for the maintenance of geno...

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Detalhes bibliográficos
Main Authors: Lin, Shiaw-Yih, Liang, Yulong, Li, Kaiyi
Formato: Artigo
Idioma:Inglês
Publicado em: Yonsei University College of Medicine 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852782/
https://ncbi.nlm.nih.gov/pubmed/20376879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2010.51.3.295
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