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Mcph1/Brit1 deficiency promotes genomic instability and tumor formation in a mouse model
MCPH1, also known as BRIT1, has recently been identified as a novel key regulatory gene of the DNA damage response pathway. MCPH1 is located on human chromosome 8p23.1, where human cancers frequently show loss of heterozygosity. As such, MCPH1 is aberrantly expressed in many malignancies, including...
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| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4417661/ https://ncbi.nlm.nih.gov/pubmed/25362854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.367 |
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