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BRIT1/MCPH1 Links Chromatin Remodeling to DNA Damage Response

To detect and repair damaged DNA, DNA damage response proteins need to overcome the barrier of condensed chromatin to gain access to DNA lesions1. ATP-dependent chromatin remodeling is one of the fundamental mechanisms used by cells to relax chromatin in DNA repair2–3. However, the mechanism mediati...

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Detalhes bibliográficos
Main Authors: Peng, Guang, Yim, Eun-Kyoung, Dai, Hui, Jackson, Andrew P., van der Burgt, Ineke, Pan, Mei-Ren, Hu, Ruozhen, Li, Kaiyi, Lin, Shiaw-Yih
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714531/
https://ncbi.nlm.nih.gov/pubmed/19525936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1895
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