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BRIT1/MCPH1 Links Chromatin Remodeling to DNA Damage Response

To detect and repair damaged DNA, DNA damage response proteins need to overcome the barrier of condensed chromatin to gain access to DNA lesions1. ATP-dependent chromatin remodeling is one of the fundamental mechanisms used by cells to relax chromatin in DNA repair2–3. However, the mechanism mediati...

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Autores principales: Peng, Guang, Yim, Eun-Kyoung, Dai, Hui, Jackson, Andrew P., van der Burgt, Ineke, Pan, Mei-Ren, Hu, Ruozhen, Li, Kaiyi, Lin, Shiaw-Yih
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714531/
https://ncbi.nlm.nih.gov/pubmed/19525936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1895
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