Probing the Telomere Damage Response

Por Rai, Rekha, Chang, Sandy
Publicado em 2011

TRF2-RAP1 is required to protect telomeres from engaging in homologous recombination-mediated deletions and fusions

Por Rai, Rekha, Chen, Yong, Lei, Ming, Chang, Sandy
Publicado no Nat Commun (2016)

BRIT1/MCPH1 is a DNA damage responsive protein that regulates the Brca1–Chk1 pathway, implicating checkpoint dysfunction in microcephaly

Por Lin, Shiaw-Yih, Rai, Rekha, Li, Kaiyi, Xu, Zhi-Xiang, Elledge, Stephen J.
Publicado em 2005

The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres

Por Rai, Rekha, Zheng, Hong, He, Hua, Luo, Ying, Multani, Asha, Carpenter, Phillip B, Chang, Sandy
Publicado em 2010

Differential regulation of centrosome integrity by DNA damage response proteins

Por Rai, Rekha, Phadnis, Ashwini, Haralkar, Sharda, Badwe, Rajendra A., Dai, Hui, Li, Kaiyi, Lin, Shiaw-Yih
Publicado em 2008

The E3 ubiquitin ligase RNF8 stabilizes TPP1 to promote telomere end protection

Por Rai, Rekha, Li, Ju-Mei, Zheng, Hong, Lok, Gabriel Tsz-Mei, Deng, Yu, Huen, Michael, Chen, Junjie, Jin, Jianping, Chang, Sandy
Publicado em 2011

TERRA and hnRNPA1 Orchestrate an RPA-to-POT1 Switch on Telomeric Single-Stranded DNA

Por Flynn, Rachel Litman, Centore, Richard C., O’Sullivan, Roderick J., Rai, Rekha, Tse, Alice, Songyang, Zhou, Chang, Sandy, Karlseder, Jan, Zou, Lee
Publicado em 2011

BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer

Por Rai, Rekha, Dai, Hui, Multani, Asha S., Li, Kaiyi, Chin, Koei, Gray, Joe, Lahad, John P., Liang, Jiyong, Mills, Gordon B., Meric-Bernstam, Funda, Lin, Shiaw-Yih
Publicado em 2006

A Conserved Motif within RAP1 Plays Diversified Roles in Telomere Protection and Regulation in Different Organisms

Por Chen, Yong, Rai, Rekha, Zhou, Zi-Ren, Kanoh, Junko, Ribeyre, Cyril, Yang, Yuting, Zheng, Hong, Damay, Pascal, Wang, Feng, Tsujii, Hisayo, Hiraoka, Yasushi, Shore, David, Hu, Hong-Yu, Chang, Sandy, Lei, Ming
Publicado em 2011

Structural insights into POT1-TPP1 interaction and POT1 C-terminal mutations in human cancer

Por Chen, Cong, Gu, Peili, Wu, Jian, Chen, Xianyun, Niu, Shuangshuang, Sun, Hong, Wu, Lijie, Li, Na, Peng, Junhui, Shi, Shaohua, Fan, Cuiying, Huang, Min, Wong, Catherine C. L., Gong, Qingguo, Kumar-Sinha, Chandan, Zhang, Rongguang, Pusztai, Lajos, Rai, Rekha, Chang, Sandy, Lei, Ming
Publicado no Nat Commun (2017)