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TRF2-RAP1 is required to protect telomeres from engaging in homologous recombination-mediated deletions and fusions
Repressor/activator protein 1 (RAP1) is a highly conserved telomere-interacting protein. Yeast Rap1 protects telomeres from non-homologous end joining (NHEJ), plays important roles in telomere length control and is involved in transcriptional gene regulation. However, a role for mammalian RAP1 in te...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4785230/ https://ncbi.nlm.nih.gov/pubmed/26941064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10881 |
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