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The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres
Repair of DNA double-stranded breaks (DSBs) is crucial for the maintenance of genome stability. DSBs are repaired by either error prone non-homologous end-joining (NHEJ) or error-free homologous recombination. NHEJ precedes either by a classic, Lig4-dependent process (C-NHEJ) or an alternative, Lig4...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2928694/ https://ncbi.nlm.nih.gov/pubmed/20588252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.142 |
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