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Role of mammalian Mre11 in classical and alternative non-homologous end joining
The mammalian Mre11-Rad50-Nbs1 (MRN) complex coordinates double strand break (DSB) signaling with repair by homologous recombination and is associated with the H2A.X chromatin response to DSBs, but its role in non-homologous end joining (NHEJ) is less clear. Here we show that Mre11 promotes efficien...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2730592/ https://ncbi.nlm.nih.gov/pubmed/19633669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1640 |
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