The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres

Repair of DNA double-stranded breaks (DSBs) is crucial for the maintenance of genome stability. DSBs are repaired by either error prone non-homologous end-joining (NHEJ) or error-free homologous recombination. NHEJ precedes either by a classic, Lig4-dependent process (C-NHEJ) or an alternative, Lig4...

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Bibliografiske detaljer
Main Authors: Rai, Rekha, Zheng, Hong, He, Hua, Luo, Ying, Multani, Asha, Carpenter, Phillip B, Chang, Sandy
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928694/
https://ncbi.nlm.nih.gov/pubmed/20588252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.142
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