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POT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombination

POT1 (protection of telomere 1) is a highly conserved single-stranded telomeric binding protein that is essential for telomere end protection. Here, we report the cloning and characterization of a second member of the mouse POT family. POT1b binds telomeric DNA via conserved DNA binding oligonucleot...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: He, Hua, Multani, Asha S, Cosme-Blanco, Wilfredo, Tahara, Hidetoshi, Ma, Jin, Pathak, Sen, Deng, Yibin, Chang, Sandy
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1630418/
https://ncbi.nlm.nih.gov/pubmed/17053789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601294
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