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Probing the Telomere Damage Response
Telomere dysfunctions, rendered through replicative attrition of telomeric DNA or due to the inhibition of shelterin components, are recognized as DNA double stranded breaks (DSBs) by the DNA damage repair (DDR) pathway. This leads to the activation of DNA damage checkpoint sensors including the Mre...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3690558/ https://ncbi.nlm.nih.gov/pubmed/21461819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-092-8_14 |
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