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Determinants of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H(2) synthases
Acetaminophen has antipyretic and analgesic properties yet differs from the nonsteroidal antiinflammatory drugs and inhibitors of prostaglandin H synthase (PGHS)-2 by exhibiting little effect on platelets or inflammation. We find parallel selectivity at a cellular level; acetaminophen inhibits PGHS...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The National Academy of Sciences
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC124540/ https://ncbi.nlm.nih.gov/pubmed/12011469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102588199 |
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