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Binding strength and activation state of single fibrinogen-integrin pairs on living cells

Integrin activation states determine the ability of these receptors to mediate cell–matrix and cell–cell interactions. The prototypic example of this phenomenon is the platelet integrin, αIIbβ3. In unstimulated platelets, αIIbβ3 is inactive, whereas exposing platelets to an agonist such as ADP or th...

詳細記述

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書誌詳細
主要な著者: Litvinov, Rustem I., Shuman, Henry, Bennett, Joel S., Weisel, John W.
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC124247/
https://ncbi.nlm.nih.gov/pubmed/12032299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.112194999
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