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Binding strength and activation state of single fibrinogen-integrin pairs on living cells

Integrin activation states determine the ability of these receptors to mediate cell–matrix and cell–cell interactions. The prototypic example of this phenomenon is the platelet integrin, αIIbβ3. In unstimulated platelets, αIIbβ3 is inactive, whereas exposing platelets to an agonist such as ADP or th...

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Hlavní autoři: Litvinov, Rustem I., Shuman, Henry, Bennett, Joel S., Weisel, John W.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC124247/
https://ncbi.nlm.nih.gov/pubmed/12032299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.112194999
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