Загрузка...
Multi-Step Fibrinogen Binding to the Integrin αIIbβ3 Detected Using Force Spectroscopy
The regulated ability of integrin αIIbβ3 to bind fibrinogen plays a crucial role in platelet aggregation and hemostasis. We have developed a model system based on laser tweezers, enabling us to measure specific rupture forces needed to separate single receptor-ligand complexes. First of all, we perf...
Сохранить в:
| Главные авторы: | , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Biophysical Society
2005
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366781/ https://ncbi.nlm.nih.gov/pubmed/16040750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.061887 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|