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Unique transmembrane domain interactions differentially modulate integrin αvβ3 and αIIbβ3 function
Lateral transmembrane (TM) helix–helix interactions between single-span membrane proteins play an important role in the assembly and signaling of many cell-surface receptors. Often, these helices contain two highly conserved yet distinct interaction motifs, arranged such that the motifs cannot be en...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6589676/ https://ncbi.nlm.nih.gov/pubmed/31160446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904867116 |
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