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Oligomerization of the integrin αIIbβ3: Roles of the transmembrane and cytoplasmic domains

Integrins are a family of α/β heterodimeric membrane proteins, which mediate cell–cell and cell–matrix interactions. The molecular mechanisms by which integrins are activated and cluster are currently poorly understood. One hypothesis posits that the cytoplasmic tails of the α and β subunits interac...

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Detalhes bibliográficos
Main Authors: Li, Renhao, Babu, Charles R., Lear, James D., Wand, A. Joshua, Bennett, Joel S., DeGrado, William F.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC60076/
https://ncbi.nlm.nih.gov/pubmed/11606749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.221463098
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