Oligomerization of the integrin αIIbβ3: Roles of the transmembrane and cytoplasmic domains

Integrins are a family of α/β heterodimeric membrane proteins, which mediate cell–cell and cell–matrix interactions. The molecular mechanisms by which integrins are activated and cluster are currently poorly understood. One hypothesis posits that the cytoplasmic tails of the α and β subunits interac...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Li, Renhao, Babu, Charles R., Lear, James D., Wand, A. Joshua, Bennett, Joel S., DeGrado, William F.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60076/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11606749/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.221463098
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