Unique transmembrane domain interactions differentially modulate integrin αvβ3 and αIIbβ3 function

Lateral transmembrane (TM) helix–helix interactions between single-span membrane proteins play an important role in the assembly and signaling of many cell-surface receptors. Often, these helices contain two highly conserved yet distinct interaction motifs, arranged such that the motifs cannot be en...

Full description

Saved in:
Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Litvinov, Rustem I., Mravic, Marco, Zhu, Hua, Weisel, John W., DeGrado, William F., Bennett, Joel S.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2019
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589676/
https://ncbi.nlm.nih.gov/pubmed/31160446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904867116
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items