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The Platelet Integrin αIIbβ3 Differentially Interacts with Fibrin Versus Fibrinogen
Fibrinogen binding to the integrin αIIbβ3 mediates platelet aggregation and spreading on fibrinogen-coated surfaces. However, in vivo αIIbβ3 activation and fibrinogen conversion to fibrin occur simultaneously, although the relative contributions of fibrinogen versus fibrin to αIIbβ3-mediated platele...
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| Udgivet i: | J Biol Chem |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4824994/ https://ncbi.nlm.nih.gov/pubmed/26867579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.706861 |
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