Resolving Two-dimensional Kinetics of the Integrin αIIbβ3-Fibrinogen Interactions Using Binding-Unbinding Correlation Spectroscopy

Using a combined experimental and theoretical approach named binding-unbinding correlation spectroscopy (BUCS), we describe the two-dimensional kinetics of interactions between fibrinogen and the integrin αIIbβ3, the ligand-receptor pair essential for platelet function during hemostasis and thrombos...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Litvinov, Rustem I., Mekler, Andrey, Shuman, Henry, Bennett, Joel S., Barsegov, Valeri, Weisel, John W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Molecular Biophysics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471694/
https://ncbi.nlm.nih.gov/pubmed/22893701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.404848
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky