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Binding strength and activation state of single fibrinogen-integrin pairs on living cells
Integrin activation states determine the ability of these receptors to mediate cell–matrix and cell–cell interactions. The prototypic example of this phenomenon is the platelet integrin, αIIbβ3. In unstimulated platelets, αIIbβ3 is inactive, whereas exposing platelets to an agonist such as ADP or th...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The National Academy of Sciences
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC124247/ https://ncbi.nlm.nih.gov/pubmed/12032299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.112194999 |
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