Effect of Deletion or Overexpression of the 19-Kilodalton Lipoprotein Rv3763 on the Innate Response to Mycobacterium tuberculosis

The 19-kDa lipoprotein of Mycobacterium tuberculosis is an important target of the innate immune response. To investigate the immune biology of this antigen in the context of the whole bacillus, we derived a recombinant M. tuberculosis H37Rv that lacked the 19-kDa-lipoprotein gene (Δ19) and compleme...

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Bibliographic Details
Main Authors: Stewart, Graham R., Wilkinson, Katalin A., Newton, Sandra M., Sullivan, Susan M., Neyrolles, Olivier, Wain, John R., Patel, Janisha, Pool, Kara-Lee, Young, Douglas B., Wilkinson, Robert J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1230982/
https://ncbi.nlm.nih.gov/pubmed/16177361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.10.6831-6837.2005
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