Prolonged Toll-Like Receptor Signaling by Mycobacterium tuberculosis and Its 19-Kilodalton Lipoprotein Inhibits Gamma Interferon-Induced Regulation of Selected Genes in Macrophages

Infection of macrophages with Mycobacterium tuberculosis or exposure to M. tuberculosis 19-kDa lipoprotein for >16 h inhibits gamma interferon (IFN-γ)-induced major histocompatibility complex class II (MHC-II) expression by a mechanism involving Toll-like receptors (TLRs). M. tuberculosis was fou...

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Detalhes bibliográficos
Main Authors: Pai, Rish K., Pennini, Meghan E., Tobian, Aaron A. R., Canaday, David H., Boom, W. Henry, Harding, Clifford V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC523004/
https://ncbi.nlm.nih.gov/pubmed/15501793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.11.6603-6614.2004
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