Prolonged Toll-Like Receptor Signaling by Mycobacterium tuberculosis and Its 19-Kilodalton Lipoprotein Inhibits Gamma Interferon-Induced Regulation of Selected Genes in Macrophages

Infection of macrophages with Mycobacterium tuberculosis or exposure to M. tuberculosis 19-kDa lipoprotein for >16 h inhibits gamma interferon (IFN-γ)-induced major histocompatibility complex class II (MHC-II) expression by a mechanism involving Toll-like receptors (TLRs). M. tuberculosis was fou...

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Bibliografiska uppgifter
Huvudupphovsmän: Pai, Rish K., Pennini, Meghan E., Tobian, Aaron A. R., Canaday, David H., Boom, W. Henry, Harding, Clifford V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2004
Ämnen:
Host Response and Inflammation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC523004/
https://ncbi.nlm.nih.gov/pubmed/15501793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.11.6603-6614.2004
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