Effect of Deletion or Overexpression of the 19-Kilodalton Lipoprotein Rv3763 on the Innate Response to Mycobacterium tuberculosis

The 19-kDa lipoprotein of Mycobacterium tuberculosis is an important target of the innate immune response. To investigate the immune biology of this antigen in the context of the whole bacillus, we derived a recombinant M. tuberculosis H37Rv that lacked the 19-kDa-lipoprotein gene (Δ19) and compleme...

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Detalhes bibliográficos
Main Authors: Stewart, Graham R., Wilkinson, Katalin A., Newton, Sandra M., Sullivan, Susan M., Neyrolles, Olivier, Wain, John R., Patel, Janisha, Pool, Kara-Lee, Young, Douglas B., Wilkinson, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1230982/
https://ncbi.nlm.nih.gov/pubmed/16177361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.10.6831-6837.2005
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