Effect of Deletion or Overexpression of the 19-Kilodalton Lipoprotein Rv3763 on the Innate Response to Mycobacterium tuberculosis

The 19-kDa lipoprotein of Mycobacterium tuberculosis is an important target of the innate immune response. To investigate the immune biology of this antigen in the context of the whole bacillus, we derived a recombinant M. tuberculosis H37Rv that lacked the 19-kDa-lipoprotein gene (Δ19) and compleme...

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Hlavní autoři: Stewart, Graham R., Wilkinson, Katalin A., Newton, Sandra M., Sullivan, Susan M., Neyrolles, Olivier, Wain, John R., Patel, Janisha, Pool, Kara-Lee, Young, Douglas B., Wilkinson, Robert J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1230982/
https://ncbi.nlm.nih.gov/pubmed/16177361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.10.6831-6837.2005
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