Understanding immune protection against tuberculosis using RNA expression profiling

por von Both, Ulrich, Kaforou, Myrsini, Levin, Michael, Newton, Sandra M.
Publicado en Vaccine (2015)

Galleria mellonella: An Infection Model for Screening Compounds Against the Mycobacterium tuberculosis Complex

por Asai, Masanori, Li, Yanwen, Khara, Jasmeet Singh, Robertson, Brian D., Langford, Paul R., Newton, Sandra M.
Publicado en Front Microbiol (2019)

Innate Immune Responses of Galleria mellonella to Mycobacterium bovis BCG Challenge Identified Using Proteomic and Molecular Approaches

por Asai, Masanori, Sheehan, Gerard, Li, Yanwen, Robertson, Brian D., Kavanagh, Kevin, Langford, Paul R., Newton, Sandra M.
Publicado en Front Cell Infect Microbiol (2021)

A novel biosafety level 2 compliant tuberculosis infection model using a ΔleuDΔpanCD double auxotroph of Mycobacterium tuberculosis H37Rv and Galleria mellonella

por Asai, Masanori, Li, Yanwen, Spiropoulos, John, Cooley, William, Everest, David, Robertson, Brian D., Langford, Paul R., Newton, Sandra M.
Publicado en Virulence (2020)

Ultra-Short Antimicrobial Peptoids Show Propensity for Membrane Activity Against Multi-Drug Resistant Mycobacterium tuberculosis

por Khara, Jasmeet Singh, Mojsoska, Biljana, Mukherjee, Devika, Langford, Paul R., Robertson, Brian D., Jenssen, Håvard, Ee, Pui Lai Rachel, Newton, Sandra M.
Publicado en Front Microbiol (2020)

Reduction of Chemokine Secretion in Response to Mycobacteria in Infliximab-Treated Patients

por Newton, Sandra M., Mackie, Sarah L., Martineau, Adrian R., Wilkinson, Katalin A., Kampmann, Beate, Fisher, Corinne, Dutta, Shouma, Levin, Michael, Wilkinson, Robert J., Pasvol, Geoffrey
Publicado 2008

Galleria mellonella - a novel infection model for the Mycobacterium tuberculosis complex

por Li, Yanwen, Spiropoulos, John, Cooley, William, Khara, Jasmeet Singh, Gladstone, Camilla A, Asai, Masanori, Bossé, Janine T, Robertson, Brian D, Newton, Sandra M, Langford, Paul R
Publicado en Virulence (2018)

Effect of Deletion or Overexpression of the 19-Kilodalton Lipoprotein Rv3763 on the Innate Response to Mycobacterium tuberculosis

por Stewart, Graham R., Wilkinson, Katalin A., Newton, Sandra M., Sullivan, Susan M., Neyrolles, Olivier, Wain, John R., Patel, Janisha, Pool, Kara-Lee, Young, Douglas B., Wilkinson, Robert J.
Publicado 2005

Neutrophil-mediated innate immune resistance to mycobacteria

por Martineau, Adrian R., Newton, Sandra M., Wilkinson, Katalin A., Kampmann, Beate, Hall, Bridget M., Nawroly, Niga, Packe, Geoffrey E., Davidson, Robert N., Griffiths, Christopher J., Wilkinson, Robert J.
Publicado 2007

Genetic determination of the effect of post-translational modification on the innate immune response to the 19 kDa lipoprotein of Mycobacterium tuberculosis

por Wilkinson, Katalin A, Newton, Sandra M, Stewart, Graham R, Martineau, Adrian R, Patel, Janisha, Sullivan, Susan M, Herrmann, Jean-Louis, Neyrolles, Olivier, Young, Douglas B, Wilkinson, Robert J
Publicado 2009

Mycobacterium tuberculosis Exploits a Molecular Off Switch of the Immune System for Intracellular Survival

por von Both, Ulrich, Berk, Maurice, Agapow, Paul-Michael, Wright, Joseph D., Git, Anna, Hamilton, Melissa Shea, Goldgof, Greg, Siddiqui, Nazneen, Bellos, Evangelos, Wright, Victoria J., Coin, Lachlan J., Newton, Sandra M., Levin, Michael
Publicado en Sci Rep (2018)

1α,25-dihydroxyvitamin D(3) inhibits matrix metalloproteinases induced by Mycobacterium tuberculosis infection

por Coussens, Anna K, Timms, Peter M, Boucher, Barbara J, Venton, Timothy R, Ashcroft, Anthony T, Skolimowska, Keira H, Newton, Sandra M, Wilkinson, Katalin A, Davidson, Robert N, Griffiths, Christopher J, Wilkinson, Robert J, Martineau, Adrian R
Publicado 2009

Innate activation of human primary epithelial cells broadens the host response to Mycobacterium tuberculosis in the airways

por Reuschl, Ann-Kathrin, Edwards, Michael R., Parker, Robert, Connell, David W., Hoang, Long, Halliday, Alice, Jarvis, Hannah, Siddiqui, Nazneen, Wright, Corrina, Bremang, Samuel, Newton, Sandra M., Beverley, Peter, Shattock, Robin J., Kon, Onn Min, Lalvani, Ajit
Publicado en PLoS Pathog (2017)

Association between Gc genotype and susceptibility to TB is dependent on vitamin D status

por Martineau, Adrian R., Leandro, Ana Cristina C. S., Anderson, Suzanne T., Newton, Sandra M., Wilkinson, Katalin A., Nicol, Mark P., Pienaar, Sandra M., Skolimowska, Keira H., Rocha, Marcia A., Rolla, Valeria C., Levin, Michael, Davidson, Robert N., Bremner, Stephen A., Griffiths, Christopher J., Eley, Brian S., Bonecini-Almeida, M. Glória, Wilkinson, Robert J.
Publicado 2009

Azithromycin blocks autophagy and may predispose cystic fibrosis patients to mycobacterial infection

por Renna, Maurizio, Schaffner, Catherine, Brown, Karen, Shang, Shaobin, Tamayo, Marcela Henao, Hegyi, Krisztina, Grimsey, Neil J., Cusens, David, Coulter, Sarah, Cooper, Jason, Bowden, Anne R., Newton, Sandra M., Kampmann, Beate, Helm, Jennifer, Jones, Andrew, Haworth, Charles S., Basaraba, Randall J., DeGroote, Mary Ann, Ordway, Diane J., Rubinsztein, David C., Floto, R. Andres
Publicado 2011

Childhood tuberculosis is associated with decreased abundance of T cell gene transcripts and impaired T cell function

por Hemingway, Cheryl, Berk, Maurice, Anderson, Suzanne T., Wright, Victoria J., Hamilton, Shea, Eleftherohorinou, Hariklia, Kaforou, Myrsini, Goldgof, Greg M., Hickman, Katy, Kampmann, Beate, Schoeman, Johan, Eley, Brian, Beatty, David, Pienaar, Sandra, Nicol, Mark P., Griffiths, Michael J., Waddell, Simon J., Newton, Sandra M., Coin, Lachlan J., Relman, David A., Montana, Giovanni, Levin, Michael
Publicado en PLoS One (2017)

A deletion defining a common Asian lineage of Mycobacterium tuberculosis associates with immune subversion

por Newton, Sandra M., Smith, Rebecca J., Wilkinson, Katalin A., Nicol, Mark P., Garton, Natalie J., Staples, Karl J., Stewart, Graham R., Wain, John R., Martineau, Adrian R., Fandrich, Sarah, Smallie, Timothy, Foxwell, Brian, Al-Obaidi, Ahmed, Shafi, Jamila, Rajakumar, Kumar, Kampmann, Beate, Andrew, Peter W., Ziegler-Heitbrock, Loems, Barer, Michael R., Wilkinson, Robert J.
Publicado 2006

Functional drug screening reveals anticonvulsants as enhancers of mTOR-independent autophagic killing of Mycobacterium tuberculosis through inositol depletion

por Schiebler, Mark, Brown, Karen, Hegyi, Krisztina, Newton, Sandra M, Renna, Maurizio, Hepburn, Lucy, Klapholz, Catherine, Coulter, Sarah, Obregón-Henao, Andres, Henao Tamayo, Marcela, Basaraba, Randall, Kampmann, Beate, Henry, Katherine M, Burgon, Joseph, Renshaw, Stephen A, Fleming, Angeleen, Kay, Robert R, Anderson, Karen E, Hawkins, Phillip T, Ordway, Diane J, Rubinsztein, David C, Floto, Rodrigo Andres
Publicado en EMBO Mol Med (2015)