1α,25-dihydroxyvitamin D(3) inhibits matrix metalloproteinases induced by Mycobacterium tuberculosis infection

Matrix metalloproteinases (MMP) can degrade all components of pulmonary extracellular matrix. Mycobacterium tuberculosis induces production of a number of these enzymes by human macrophages, and these are implicated in the pathogenesis of pulmonary cavitation in tuberculosis. The active metabolite o...

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Détails bibliographiques
Auteurs principaux: Coussens, Anna K, Timms, Peter M, Boucher, Barbara J, Venton, Timothy R, Ashcroft, Anthony T, Skolimowska, Keira H, Newton, Sandra M, Wilkinson, Katalin A, Davidson, Robert N, Griffiths, Christopher J, Wilkinson, Robert J, Martineau, Adrian R
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2009
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729531/
https://ncbi.nlm.nih.gov/pubmed/19178594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.03024.x
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