1α,25-dihydroxyvitamin D(3) inhibits matrix metalloproteinases induced by Mycobacterium tuberculosis infection

Matrix metalloproteinases (MMP) can degrade all components of pulmonary extracellular matrix. Mycobacterium tuberculosis induces production of a number of these enzymes by human macrophages, and these are implicated in the pathogenesis of pulmonary cavitation in tuberculosis. The active metabolite o...

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Detalhes bibliográficos
Main Authors: Coussens, Anna K, Timms, Peter M, Boucher, Barbara J, Venton, Timothy R, Ashcroft, Anthony T, Skolimowska, Keira H, Newton, Sandra M, Wilkinson, Katalin A, Davidson, Robert N, Griffiths, Christopher J, Wilkinson, Robert J, Martineau, Adrian R
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729531/
https://ncbi.nlm.nih.gov/pubmed/19178594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.03024.x
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