The effects of 1α,25-dihydroxyvitamin D(3) on matrix metalloproteinase and prostaglandin E(2) production by cells of the rheumatoid lesion

INTRODUCTION: 1α,25-dihydroxyvitamin D(3) [1α,25(OH)(2)D(3)], the biologically active metabolite of vitamin D(3), acts through an intracellular vitamin D receptor (VDR) and has several immunostimulatory effects. Animal studies have shown that production of some matrix metalloproteinases (MMPs) may b...

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Autors principals: Tetlow, Lynne C, Woolley, David E
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 1999
Matèries:
Primary Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC17774/
https://ncbi.nlm.nih.gov/pubmed/11056661
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