Effects of induced mast cell activation on prostaglandin E and metalloproteinase production by rheumatoid synovial tissue in vitro

OBJECTIVE—To determine whether induced mast cell activation/degranulation in rheumatoid synovial explants modulates the production of prostaglandin E (PGE(2)), and the matrix metalloproteinases (MMPs) collagenase 1, gelatinase A, and stromelysin 1.
METHODS—Synovial explant cultures were treated eith...

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Detalhes bibliográficos
Main Authors: Tetlow, L, Harper, N, Dunningham, T, Morris, M, Bertfield, H, Woolley, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Extended Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1752465/
https://ncbi.nlm.nih.gov/pubmed/9536819
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