Azithromycin blocks autophagy and may predispose cystic fibrosis patients to mycobacterial infection

Azithromycin is a potent macrolide antibiotic with poorly understood antiinflammatory properties. Long-term use of azithromycin in patients with chronic inflammatory lung diseases, such as cystic fibrosis (CF), results in improved outcomes. Paradoxically, a recent study reported that azithromycin us...

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Main Authors: Renna, Maurizio, Schaffner, Catherine, Brown, Karen, Shang, Shaobin, Tamayo, Marcela Henao, Hegyi, Krisztina, Grimsey, Neil J., Cusens, David, Coulter, Sarah, Cooper, Jason, Bowden, Anne R., Newton, Sandra M., Kampmann, Beate, Helm, Jennifer, Jones, Andrew, Haworth, Charles S., Basaraba, Randall J., DeGroote, Mary Ann, Ordway, Diane J., Rubinsztein, David C., Floto, R. Andres
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Clinical Investigation 2011
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163956/
https://ncbi.nlm.nih.gov/pubmed/21804191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI46095
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