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Autophagic substrate clearance requires activity of the syntaxin-5 SNARE complex
Autophagy is a lysosome-dependent cellular catabolic mechanism that mediates the turnover of intracellular organelles and long-lived proteins. Reduced autophagic activity has been shown to lead to the accumulation of misfolded proteins in neurons and might be involved in chronic neurodegenerative di...
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| Main Authors: | , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Company of Biologists
2011
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3022001/ https://ncbi.nlm.nih.gov/pubmed/21242315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.076489 |
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