Gene expression profiling in conjunction with physiological rescues of IKKα null cells with Wt. or mutant IKKα reveals distinct classes of IKKα/NF-κB dependent genes

Eitemau Tebyg

• IKKα, IKKβ and NEMO/IKKγ are each required for the NF-κB mediated inflammatory response program
  gan: LI, Xiang, et al.
  Cyhoeddwyd: (2002)
• Sustained NF-κB activation produces a short-term cell proliferation block in conjunction with repressing effectors of cell cycle progression controlled by E2F or FoxM1
  gan: Penzo, Marianna, et al.
  Cyhoeddwyd: (2009)
• Rescue of skeletal muscle α-actin–null mice by cardiac (fetal) α-actin
  gan: Nowak, Kristen J., et al.
  Cyhoeddwyd: (2009)
• Differential requirements for IKKα and IKKβ in the differentiation of primary human osteoarthritic chondrocytes
  gan: Olivotto, Eleonora, et al.
  Cyhoeddwyd: (2008)
• Functional Isoforms of IκB Kinase α (IKKα) Lacking Leucine Zipper and Helix-Loop-Helix Domains Reveal that IKKα and IKKβ Have Different Activation Requirements
  gan: McKenzie, Fergus R., et al.
  Cyhoeddwyd: (2000)