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IKKα, IKKβ and NEMO/IKKγ are each required for the NF-κB mediated inflammatory response program

The IKKβ and NEMO/IKKγ subunits of the NF-κB activating signalsome complex are known to be essential for activating NF-κB by inflammatory and other stress-like stimuli. However, the IKKα subunit is believed to be dispensable for the latter responses and instead functions as an in vivo mediator of ot...

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Autors principals: LI, Xiang, MASSA, Paul E., HANIDU, Adedayo, PEET, Gregory W., ARO, Patrick, Savitt, Ann, MISCHE, Sheenah, LI, Jun, MARCU, Kenneth B.
Format: Artigo
Idioma:Inglês
Publicat: 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201411/
https://ncbi.nlm.nih.gov/pubmed/12221085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M205165200
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