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IKKα, IKKβ and NEMO/IKKγ are each required for the NF-κB mediated inflammatory response program
The IKKβ and NEMO/IKKγ subunits of the NF-κB activating signalsome complex are known to be essential for activating NF-κB by inflammatory and other stress-like stimuli. However, the IKKα subunit is believed to be dispensable for the latter responses and instead functions as an in vivo mediator of ot...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1201411/ https://ncbi.nlm.nih.gov/pubmed/12221085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M205165200 |
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