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IKKα, IKKβ and NEMO/IKKγ are each required for the NF-κB mediated inflammatory response program
The IKKβ and NEMO/IKKγ subunits of the NF-κB activating signalsome complex are known to be essential for activating NF-κB by inflammatory and other stress-like stimuli. However, the IKKα subunit is believed to be dispensable for the latter responses and instead functions as an in vivo mediator of ot...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1201411/ https://ncbi.nlm.nih.gov/pubmed/12221085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M205165200 |
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