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TNFα- and IKKβ-mediated TANK/I-TRAF phosphorylation: implications for interaction with NEMO/IKKγ and NF-κB activation

Pro-inflammatory cytokines trigger signalling cascades leading to NF-κB (nuclear factor-κB)-dependent gene expression through IKK [IκB (inhibitory κB) kinase]-dependent phosphorylation and subsequent degradation of the IκB proteins and via induced phosphorylation of p65. These signalling pathways re...

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Bibliografske podrobnosti
Main Authors: Bonif, Marianne, Meuwis, Marie-Alice, Close, Pierre, Benoit, Valérie, Heyninck, Karen, Chapelle, Jean-Paul, Bours, Vincent, Merville, Marie-Paule, Piette, Jacques, Beyaert, Rudi, Chariot, Alain
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383709/
https://ncbi.nlm.nih.gov/pubmed/16336209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051659
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