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NEMO/IKKγ regulates an early NF-κB-independent cell death checkpoint during TNF signaling

TNF receptor 1 (TNFR1) ligation can result in cell survival or cell death. What determines which of the two opposing responses is triggered is not fully understood. The current model suggests that it is the activation of the NF-κB pathway and its induction of pro-survival genes, or the lack thereof,...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Legarda-Addison, Diana, Hase, Hidenori, O'Donnell, Marie Anne, Ting, Adrian T.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728158/
https://ncbi.nlm.nih.gov/pubmed/19373245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2009.41
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