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NEMO Inhibits Programmed Necrosis in an NFκB-Independent Manner by Restraining RIP1
TNF can trigger two opposing responses: cell survival and cell death. TNFR1 activates caspases that orchestrate apoptosis but some cell types switch to a necrotic death when treated with caspase inhibitors. Several genes that are required to orchestrate cell death by programmed necrosis have been id...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3406058/ https://ncbi.nlm.nih.gov/pubmed/22848449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041238 |
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