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Non-homologous end joining, but not homologous recombination, enables survival for cells exposed to a histone deacetylase inhibitor
Non-homologous end joining (NHEJ) and homologous recombination (HR) are pathways that repair DNA double-strand breaks (DSBs). In Saccharomyces cerevisiae, the repair of these breaks is influenced by histone acetylation. Therefore, we tested mammalian cells deleted for NHEJ (Ku80 or DNA Ligase IV) or...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1226312/ https://ncbi.nlm.nih.gov/pubmed/16177181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki821 |
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