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Histone Deacetylases 9 and 10 Are Required for Homologous Recombination

We tested the role of histone deacetylases (HDACs) in the homologous recombination process. A tissue-culture based homology-directed repair assay was used in which repair of a double-stranded break by homologous recombination results in gene conversion of an inactive GFP allele to an active GFP gene...

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Autors principals: Kotian, Shweta, Liyanarachchi, Sandhya, Zelent, Arthur, Parvin, Jeffrey D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048658/
https://ncbi.nlm.nih.gov/pubmed/21247901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C110.194233
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