Histone Deacetylase 10 Regulates DNA Mismatch Repair and May Involve the Deacetylation of MutS Homolog 2

MutS homolog 2 (MSH2) is an essential DNA mismatch repair (MMR) protein. It interacts with MSH6 or MSH3 to form the MutSα or MutSβ complex, respectively, which recognize base-base mispairs and insertions/deletions and initiate the repair process. Mutation or dysregulation of MSH2 causes genomic inst...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Radhakrishnan, Rangasudhagar, Li, Yixuan, Xiang, Shengyan, Yuan, Fenghua, Yuan, Zhigang, Telles, Elphine, Fang, Jia, Coppola, Domenico, Shibata, David, Lane, William S., Zhang, Yanbin, Zhang, Xiaohong, Seto, Edward
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
DNA and Chromosomes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4566250/
https://ncbi.nlm.nih.gov/pubmed/26221039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.612945
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