Histone deacetylase 9 regulates breast cancer cell proliferation and the response to histone deacetylase inhibitors

Histone lysine acetylation is an epigenetic mark regulated by histone acetyltransferases and histone deacetylases (HDAC) which plays an important role in tumorigenesis. In this study, we observed a strong overexpression of class IIa HDAC9, at the mRNA and protein levels, in the most aggressive human...

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Vydáno v:Oncotarget
Hlavní autoři: Lapierre, Marion, Linares, Aurélien, Dalvai, Mathieu, Duraffourd, Céline, Bonnet, Sandrine, Boulahtouf, Abdelhay, Rodriguez, Carmen, Jalaguier, Stéphan, Assou, Said, Orsetti, Beatrice, Balaguer, Patrick, Maudelonde, Thierry, Blache, Philippe, Bystricky, Kerstin, Boulle, Nathalie, Cavaillès, Vincent
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991412/
https://ncbi.nlm.nih.gov/pubmed/26930713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7564
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