Histone deacetylase 9 regulates breast cancer cell proliferation and the response to histone deacetylase inhibitors

Histone lysine acetylation is an epigenetic mark regulated by histone acetyltransferases and histone deacetylases (HDAC) which plays an important role in tumorigenesis. In this study, we observed a strong overexpression of class IIa HDAC9, at the mRNA and protein levels, in the most aggressive human...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lapierre, Marion, Linares, Aurélien, Dalvai, Mathieu, Duraffourd, Céline, Bonnet, Sandrine, Boulahtouf, Abdelhay, Rodriguez, Carmen, Jalaguier, Stéphan, Assou, Said, Orsetti, Beatrice, Balaguer, Patrick, Maudelonde, Thierry, Blache, Philippe, Bystricky, Kerstin, Boulle, Nathalie, Cavaillès, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991412/
https://ncbi.nlm.nih.gov/pubmed/26930713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7564
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