Histone deacetylase 9 regulates breast cancer cell proliferation and the response to histone deacetylase inhibitors

Histone lysine acetylation is an epigenetic mark regulated by histone acetyltransferases and histone deacetylases (HDAC) which plays an important role in tumorigenesis. In this study, we observed a strong overexpression of class IIa HDAC9, at the mRNA and protein levels, in the most aggressive human...

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Udgivet i:Oncotarget
Main Authors: Lapierre, Marion, Linares, Aurélien, Dalvai, Mathieu, Duraffourd, Céline, Bonnet, Sandrine, Boulahtouf, Abdelhay, Rodriguez, Carmen, Jalaguier, Stéphan, Assou, Said, Orsetti, Beatrice, Balaguer, Patrick, Maudelonde, Thierry, Blache, Philippe, Bystricky, Kerstin, Boulle, Nathalie, Cavaillès, Vincent
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991412/
https://ncbi.nlm.nih.gov/pubmed/26930713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7564
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