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Manipulating Protein Acetylation in Breast Cancer: A Promising Approach in Combination with Hormonal Therapies?

Estrogens play an essential role in the normal physiology of the breast as well as in mammary tumorigenesis. Their effects are mediated by two nuclear estrogen receptors, ERα and β, which regulate transcription of specific genes by interacting with multiprotein complexes, including histone deacetyla...

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Detalhes bibliográficos
Main Authors: Linares, Aurélien, Dalenc, Florence, Balaguer, Patrick, Boulle, Nathalie, Cavailles, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004450/
https://ncbi.nlm.nih.gov/pubmed/21188173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/856985
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