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Manipulating Protein Acetylation in Breast Cancer: A Promising Approach in Combination with Hormonal Therapies?

Estrogens play an essential role in the normal physiology of the breast as well as in mammary tumorigenesis. Their effects are mediated by two nuclear estrogen receptors, ERα and β, which regulate transcription of specific genes by interacting with multiprotein complexes, including histone deacetyla...

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Bibliografiske detaljer
Main Authors: Linares, Aurélien, Dalenc, Florence, Balaguer, Patrick, Boulle, Nathalie, Cavailles, Vincent
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004450/
https://ncbi.nlm.nih.gov/pubmed/21188173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/856985
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