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Non-homologous end joining, but not homologous recombination, enables survival for cells exposed to a histone deacetylase inhibitor
Non-homologous end joining (NHEJ) and homologous recombination (HR) are pathways that repair DNA double-strand breaks (DSBs). In Saccharomyces cerevisiae, the repair of these breaks is influenced by histone acetylation. Therefore, we tested mammalian cells deleted for NHEJ (Ku80 or DNA Ligase IV) or...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2005
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1226312/ https://ncbi.nlm.nih.gov/pubmed/16177181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki821 |
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