Embryonic stem cells and somatic cells differ in mutation frequency and type

Pluripotent embryonic stem (ES) cells have been used to produce genetically modified mice as experimental models of human genetic diseases. Increasingly, human ES cells are being considered for their potential in the treatment of injury and disease. Here we have shown that mutation in murine ES cell...

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Cyhoeddwyd yn:	Proc Natl Acad Sci U S A
Prif Awduron:	Cervantes, Rachel B., Stringer, James R., Shao, Changshun, Tischfield, Jay A., Stambrook, Peter J.
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	National Academy of Sciences 2002
Pynciau:	Biological Sciences
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122567/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11891338/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.062527199
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