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The origin and efficient derivation of embryonic stem cells in the mouse

By explanting tissues isolated microsurgically from implanting strain 129 mouse blastocysts individually on STO feeder cells we have established that embryonic stem (ES) cells originate from the epiblast (primitive ectoderm). Isolated early epiblasts yielded ES cell lines at a substantially higher f...

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Detalhes bibliográficos
Main Authors: Brook, F. A., Gardner, R. L.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20843/
https://ncbi.nlm.nih.gov/pubmed/9159137
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