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The origin and efficient derivation of embryonic stem cells in the mouse

By explanting tissues isolated microsurgically from implanting strain 129 mouse blastocysts individually on STO feeder cells we have established that embryonic stem (ES) cells originate from the epiblast (primitive ectoderm). Isolated early epiblasts yielded ES cell lines at a substantially higher f...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Brook, F. A., Gardner, R. L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1997
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20843/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9159137/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.11.5709
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